University of Bahrain Researcher Publishes Potential Treatment for Leishmaniasis in International Journal

The researcher Hussein Saqr, Assistant Researcher and Teaching Assistant in the Department of Chemistry at the College of Science, University of Bahrain, has published his scientific study titled: “Pyridine-2,6-dicarboxylic Acid Derivatives with Potential Activity Against Leishmaniasis: Synthesis, Biological Evaluation, and Computational Studies,” in the journal Bioorganic & Medicinal Chemistry Letters on April 18, 2026. The journal is an international peer-reviewed publication issued by Elsevier and indexed in major scientific databases such as Scopus, PubMed, and Web of Science, reinforcing its status as a reputable platform for drug discovery research.

The study focuses on the design and synthesis of a new series of chemical compounds derived from pyridine-2,6-dicarboxylic acid, aiming to explore effective therapeutic agents against leishmaniasis. This disease is considered among the conditions that do not receive sufficient attention and affects millions worldwide, in the context of limited treatment options due to drug resistance and toxicity challenges, highlighting the importance of developing safer and more effective therapeutic alternatives.

The researcher, in collaboration with his team, adopted an integrated methodology combining laboratory chemical synthesis, biological evaluation of antiparasitic activity, and in-silico computational studies that simulate the interaction of compounds with molecular targets. This provides a comprehensive understanding of the mechanisms of action and future drug development potential.

This achievement represents a significant scientific contribution that reflects the advancement of research at the University of Bahrain and strengthens its presence in the international field of medicinal chemistry research, while also contributing to global efforts to develop treatments for high-priority health diseases.

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